Expression of HTLV-I antigen in cultured peripheral blood mononuclear cells from patients with HTLV-I associated myelopathy

S Minato, Y Itoyama, I Goto, N Yamamoto - Journal of the neurological …, 1988 - Elsevier
Abstract The HTLV-I antigen (Ag) was detected in short-term cultured peripheral blood
mononuclear cells (PBMNC) from 44% of patients with HTLV-I-associated myelopathy
(HAM), using the indirect immunofluorescence method. The HTLV-I Ag-positive cells
accounted for less than 4% of cultured PBMNC in all but one case. The kinetics and
mechanism of HTLV-I Ag expression in cultured cells were these studied in this individual
with about 20% positive cells. HTLV-I Ag was 0.3% at 6 h after the culture and the number of …